How To Take LYRICA® (pregabalin) CV | Dosing | Safety Info
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Knowing How to Take LYRICA
Can Help You Get the Most From Treatment

There are things you can do when taking LYRICA to get the most from your treatment. It’s important to work closely with your doctor if you are not feeling the relief you hoped for or if you are experiencing side effects. Your doctor may be able to help by adjusting your dose. So now’s a great time to learn about taking LYRICA and working with your doctor to find the right dosage strength for you.

It’s Important to Understand How to Take LYRICA From Day 1



How do I take LYRICA?


Take LYRICA every day as prescribed by your doctor. Here are a few ways to help make sure you take LYRICA the right way:
Try to take LYRICA at the same times each day
Consider taking LYRICA in combination with other daily activities, such as eating meals or brushing your teeth
You can take LYRICA with or without food
Keep in mind. If you aren’t feeling the results you expected or if you are experiencing side effects, there may be things your doctor can do to help. Do not stop taking LYRICA without first talking to your doctor. Learn how to best partner with your doctor

What happens if I miss a dose?


If you miss a dose by a few hours, take it as soon as you remember. If it is close to your next dose, do not take the missed dose. Just take LYRICA at your next regular time. Do not take 2 doses at the same time.

How do I know if I’m on the right dose?


Everyone is unique and may respond to LYRICA differently. LYRICA is available in multiple strengths. Your doctor can adjust your dose to help you get the most from treatment. So it’s important to discuss your progress and any side effects you may feel with your doctor, especially in the first few weeks. Learn more about the potential side effects of LYRICA

In clinical trials, many patients who began at the recommended starting dosage and increased their dosage within the recommended ongoing dosage range had better relief.

What dose is recommended for my condition?
Take LYRICA every day as prescribed by your doctor. The chart below outlines the following for each condition: the recommended number of times per day to take LYRICA, the recommended total starting dosage, and the recommended total ongoing dosage.

  Number of times
per day to take LYRICA 		Recommended total
starting dosage 		Recommended total
ongoing dosage

Fibromyalgia

 2 150 mg/day 300 mg/day to
450 mg/day

Diabetic nerve pain

 3 150 mg/day 300 mg/day

Pain after shingles

 2 or 3
(depending on the dose) 		150 mg/day 150 mg/day to
600 mg/day*

Partial onset
seizures in adults
with epilepsy

 2 or 3
(depending on the dose) 		150 mg/day 150 mg/day to
600 mg/day

Your doctor may make adjustments according to your needs. If you have problems with kidney function, your doctor may prescribe a lower dose of LYRICA.

* Patients who do not experience sufficient pain relief following 2 to 4 weeks of treatment with 300 mg per day, and who are able to tolerate LYRICA, may be treated with up to 600 mg per day.

Do I have to keep taking LYRICA if I feel better?


LYRICA should be taken every day as prescribed by your doctor to manage your condition effectively, even if you feel better. Your symptoms may return without continued treatment.

LYRICA may cause serious allergic reactions in some people. Stop taking LYRICA and call your doctor right away if you have swelling or trouble breathing. Otherwise, do not stop taking LYRICA without first talking to your doctor.

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LYRICA is indicated to treat fibromyalgia, diabetic nerve pain, and pain after shingles. LYRICA is also indicated to treat partial onset seizures in adults with epilepsy who take 1 or more drugs for seizures.

Important Safety Information

LYRICA is not for everyone. LYRICA may cause serious, even life threatening, allergic reactions. Stop taking LYRICA and call your doctor right away if you have any signs of a serious allergic reaction. Some signs are swelling of your face, mouth, lips, gums, tongue, throat or neck or if you have any trouble breathing, or have a rash, hives or blisters.

Drugs used to treat seizures increase the risk of suicidal thoughts or behavior. LYRICA may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Call your doctor right away if you have new or worsening depression, suicidal thoughts or actions, or unusual changes in mood or behavior. If you have suicidal thoughts or actions, do not stop LYRICA without first talking to your doctor.

LYRICA may cause swelling of your hands, legs and feet, which can be serious for people with heart problems. LYRICA may cause dizziness and sleepiness. You should not drive or work with machines until you know how LYRICA affects you. Also, tell your doctor right away about muscle pain or problems along with feeling sick and feverish, or any changes in your eyesight including blurry vision or if you have any kidney problems or get dialysis.

Some of the most common side effects of LYRICA are dizziness, blurry vision, weight gain, sleepiness, trouble concentrating, swelling of your hands and feet, dry mouth, and feeling "high." If you have diabetes, tell your doctor about any skin sores.

You may have a higher chance for swelling and hives if you are also taking angiotensin converting enzyme (ACE) inhibitors so tell your doctor if you are taking these medications. You may have a higher chance of swelling of your hands or feet or gaining weight if you are also taking certain diabetes medicines. Do not drink alcohol while on LYRICA. You may have a higher chance for dizziness and sleepiness if you take LYRICA with alcohol, narcotic pain medicines, or medicines for anxiety.

Before you start LYRICA, tell your doctor if you are planning to father a child, or if you are pregnant, plan to become pregnant, or are breast-feeding. If you have had a drug or alcohol problem, you may be more likely to misuse LYRICA.

In studies, a specific type of blood vessel tumor was seen in mice, but not in rats. The meaning of these findings in humans is not known.

Do not stop taking LYRICA without talking to your doctor. If you stop suddenly you may have headaches, nausea, diarrhea or trouble sleeping and if you have epilepsy, you may have seizures more often.

View the Medication Guide

View the Full Prescribing Information
The product information provided in this site is intended only for residents of the United States. The products discussed herein may have different product labeling in different countries.

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.
Copyright © 2012 Pfizer Inc. All rights reserved. PBP01545A/291119-01